| Dates of Office | Deputy Prime Minister | Political Affiliation |
| 16 Sep 1977 - 03 Jun 1979 | The Honourable Allan MacEachen | Liberal |
| 03 Jun 1979 - 03 Mar 1980 | Vacant |
|
| 03 Mar 1980 - 30 Jun 1984 | The Honourable Allan MacEachen | Liberal |
| 30 Jun 1984 - 17 Sep 1984 | The Honourable Jean Chrétien | Liberal |
| 17 Sep 1984 - 30 Jun 1986 | The Honourable Erik Nielsen | Progressive Conservative |
| 30 Jun 1986 - 25 Jun 1993 | The Honourable Don Mazankowski | Progressive Conservative |
| 25 Jun 1993 - 04 Nov 1993 | The Honourable Jean Charest | Progressive Conservative |
| 04 Nov 1993 - 31 Apr 1996 | The Honourable Sheila Copps | Liberal |
| 31 Apr 1996 - 19 Jun 1996 | Vacant |
|
| 19 Jun 1996 - 11 Jun 1997 | The Honourable Sheila Copps | Liberal |
| 11 Jun 1997 - 15 Jan 2002 | The Honourable Herb Gray | Liberal |
| 15 Jan 2002 - 12 Dec 2003 | The Honourable John Manley | Liberal |
| 12 Dec 2003 - 06 Feb 2006 | The Honourable Anne McLellan | Liberal |
| 06 Feb 2006 - 20 Nov 2019 | Vacant |
|
| 20 Nov 2019 - 16 Dec 2024 | The Honourable Chrystia Freeland | Liberal |
| 16 Dec 2024 - | Vacant |
|